Publications

Selected Publications

Christoffel DJ, Walsh JJ, Hoerbelt P, Heifets BD, Llorach P, Lopez RC, Ramakrishnan C, Deisseroth K, Malenka RC. Selective filtering of excitatory inputs to nucleus accumbens by dopamine and serotonin. PNAS 2021June; 118 (24) e210664811

Christoffel DJ, Walsh JJ, Heifets BD, Hoerbelt P, Neuner S, Sun G, Ravikumar V K, Wu H, Halpern CH & Malenka RC. Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding. Nat Commun 2021 Apr; 12 2135.

Walsh JJ, Christoffel DJ, Wu X, Pomrenze M, Malenka RC. Dissecting neural mechanisms of prosocial behaviors. Current opinion in neurobiology 68, 9–14 (2020).

Heshmati M, Christoffel DJ, LeClair K, Cathomas F, Golden SA, Aleyasin H, Turecki G, Friedman AK, Han MH, Menard C, Russo SJ. Depression and social defeat stress are associated with inhibitory synaptic changes in the nucleus accumbens. J Neurosci 2020 Aug; 40 6228-33.

Walsh JJ, Christoffel DJ, Heifets B, Ben-Dor GA, Selimbeyoglu A, Hung LW, Deisseroth K, Malenka RC. 5-HT release in nucleus accumbens rescues social deficits in an autism mouse model. Nature 2018 Aug; 560 589-594.

Christoffel DJ, Golden SA, Walsh JJ, Guise KG, Heshmati M, Friedman AK, Dey A, Smith M, Rebusi N, Pfau M, Ables JA, Aleyasin H, Khibnik LA, Hodes GE, Ben-Dor GA, Deisseroth K, Shapiro ML, Malenka RC, Ibanez-Tallon I, Han M-H, Russo SJ. Excitatory transmission at thalamo-striatal synapses mediates susceptibility to social stress. Nature Neuroscience 2015 July; 18 962-964

Golden SA, Christoffel DJ, Heshmati M, Hodes GE, Magida J, Davis K, Cahill ME, Dias C, Ribeiro E, Ables JL, Kennedy PJ, Robison AJ,Gonzalez-Maeso J, Neve RL, Turecki G, Ghose S, Tamminga CA, Russo SJ. Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression. Nat. Medicine 2013 Mar; 19 337-44

Steinberg EE, Christoffel DJ, Deisseroth K & Malenka RC. Illuminating circuitry relevant to psychiatric disorders with optogenetics. Current opinion in neurobiology 30C, 9–16 (2014).

Christoffel, DJ, Golden SA, Dumitriu D, Robison AJ, Janssen WG, Ahn HF, Krishnan V, Reyes CM, Han M, Ables JL, Eisch AJ, Dietz DM, Ferguson D, Neve RL, Greengard P, Kim Y, Morrison JH, Russo SJ. IkappaB kinase regulates social defeat stress induced synaptic and behavioral plasticity. J. Neurosci. 2011 Jan; 31 314-21

Complete list of publications here.